Berberine is a plant alkaloid that possesses a number of powerful medicinal properties. It has traditionally been delivered as the active ingredient in goldenseal, Oregon grape and barberry extracts to provide broad-spectrum antimicrobial actions and digestive support. However, more recently its isolation and powerful application for blood sugar control, insulin resistance and cholesterol management have become evident.
When it comes to berberine’s antimicrobial actions, research has found that it effectively combats bacteria, viruses, fungi and parasites. It achieves these antimicrobial actions through multiple mechanisms including the inhibition of microbial growth, endotoxin formation, bacterial adhesion and viral replication. This allows for a truly broad-spectrum approach for patients with dysbiosis, chronic infections or exposure to multiple pathogenic microbes.
Berberine has a particularly affinity and beneficial action in the digestive tract. Evidence has shown that berberine can effectively treat symptoms of bacterial diarrhea and intestinal parasites. In addition, berberine can improve the integrity of tight junctions in the digestive tract and, therefore, positively affect intestinal permeability. Finally, berberine can regulate gastrointestinal motility and increase the gut production of butyrate, a shortchain fatty acid that provides fuel and anti-inflammatory support in the colon.
Regarding metabolic function, research has uncovered the vast application of berberine for insulin and blood sugar regulation. Double-blinded, placebo-controlled studies using berberine in those with existing medical conditions have found that it can reduce fasting blood sugar levels, insulin resistance, hemoglobin A1c, triglycerides, total cholesterol and LDL measures. Remarkably, these effects are considered comparable to oral hypoglycemic medications. Individuals with non alcoholic fatty liver have also seen comparable improvements in lipids, body mass index and insulin resistance, with significant improvements in liver fat content.
Cyto-Matrix’s Berber contains 500mg of Berberis aquifolium (Oregon grape extract) per capsule, standardized to 97% berberine content to provide therapeutic support for healthy digestion, microbial balance, blood sugar regulation and metabolic control.