Stress, insomnia and mood imbalances often clinically present together and share common pathophysiological pathways. Although hormonal inputs, genetic predispositions and biochemical individualities may vary, an overactive nervous system is a common clinical concern and treatment target. Liposomal GABA + L-Theanine by Cyto-Matrix is designed to offer two evidence-based nutrients in a unique and improved delivery system to optimally calm the nervous system.
Gamma-aminobutyric acid, most commonly referred to as GABA, is the major inhibitory neurotransmitter found in the human brain and is responsible for calming the mind under excitatory conditions. Lower brain levels of GABA have been correlated with various mood disorders, sleep concerns and other neurological disorders. Studies indicate that GABA can improve relaxation and concentration during times of stress, reduce sleep latency and increase time spent in deep sleep. Additionally, if supplemented with GABA beforehand, individuals show stable levels of salivary immunoglobulin A (IgA) and reduced cortisol levels when exposed to stress. Collectively, these mechanisms all indicate a reduced and more balanced stress response.
L-Theanine is another compound that is well-known to calm the mind and improve focus, in part through GABA receptor activation. As an amino acid naturally sourced from green tea, research has found that L-theanine can positively impact serotonin, dopamine and GABA in the brain. This ultimately leads to an increase in alpha-brain waves and a calm, yet focused, state. Clinical trials have confirmed that these actions lead to reduced stress, improved learning capacity and improved mood. L-theanine also has potential cardiovascular and detoxification benefits through cholesterol protection and increased glutathione levels. Collectively, L-theanine balances the nervous system and provides potent antioxidant support to protect the body from damage.
Liposomal GABA + L-Theanine by Cyto-Matrix has combined these two evidence-based and effective nutrients into an optimized delivery system for best clinical outcomes. Liposomal delivery systems were originally developed to optimize the pharmacokinetics and efficacy of pharmaceutical drugs. These same principles have now been applied to natural health ingredients. A liposome consists of either a single-layered or multi-layered phospholipid structure with an aqueous core. Active ingredients can be placed inside the aqueous core or within the phospholipid bilayer, where they are protected from various enzymatic and digestive processes.
Ultimately, liposomes provide improved bioavailability for active ingredients.
However, not all liposomal delivery systems are created equal. Liposomes are several hundred nanometers in size, which means that there is still a significant amount of digestion that must occur to decrease surface area and allow for proper absorption. Micelles, on the other hand, are significantly smaller and can be absorbed directly at ~20 nanometers in size.
Liposomal GABA + L-Theanine by Cyto-Matrix utilizes Cyto-Sorb, a unique and patented technology, in order to create a stable multi-layered liposome with additional micellar delivery of nutrients. These methods allow for micronutrient stability and improved bioavailability, while also promoting the delivery of active ingredients to the intestinal sites of absorption in a sustained release fashion.
Cyto-Sorb liposomal formulas are produced through a two-phase emulsion process utilizing phosphatidylcholine sourced from non-GMO sunflower, vitamin E and organic coconut vegetable glycerin. Potassium bicarbonate is strategically added to stabilize the active ingredient, prevent oxidation and improve flavour. Liposomal GABA + LTheanine by Cyto-Matrix provides 300mg of GABA and 100mg of L-theanine per teaspoon in micellar liposomal delivery for improved bioavailability and clinical efficacy. Each bottle provides 45 servings in a delicious natural orange flavour.